human grpr positive prostate cancer cell line pc 3 (ATCC)
Structured Review
![In vitro binding specificity ( A ) and cellular internalization ( B ) of [ 68 Ga]Ga-AU-RM26-M2 (black), [ 68 Ga]Ga-PKB2 (blue), and [ 68 Ga]Ga-PKB3 (red) <t>in</t> <t>PC-3</t> cells. Representative competition binding curves for nat Ga-AU-RM26-M2, nat Ga-PKB2, and nat Ga-PKB3 against [ 125 I]I-Tyr 4 -BBN in PC-3 cells ( C ). Error bars could not be visible due to low variability. Data are presented as mean ± SD, n = 3 for A and B ; n = 6 for C](https://pub-med-central-images-cdn.bioz.com/pub_med_central_ids_ending_with_9764/pmc12929764/pmc12929764__41181_2026_431_Fig3_HTML.jpg)
Human Grpr Positive Prostate Cancer Cell Line Pc 3, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 14405 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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1) Product Images from "Exploring the theranostic potential of two metabolically stable GRPR-targeting peptides labelled with Ga-68 for PET imaging"
Article Title: Exploring the theranostic potential of two metabolically stable GRPR-targeting peptides labelled with Ga-68 for PET imaging
Journal: EJNMMI Radiopharmacy and Chemistry
doi: 10.1186/s41181-026-00431-5
Figure Legend Snippet: In vitro binding specificity ( A ) and cellular internalization ( B ) of [ 68 Ga]Ga-AU-RM26-M2 (black), [ 68 Ga]Ga-PKB2 (blue), and [ 68 Ga]Ga-PKB3 (red) in PC-3 cells. Representative competition binding curves for nat Ga-AU-RM26-M2, nat Ga-PKB2, and nat Ga-PKB3 against [ 125 I]I-Tyr 4 -BBN in PC-3 cells ( C ). Error bars could not be visible due to low variability. Data are presented as mean ± SD, n = 3 for A and B ; n = 6 for C
Techniques Used: In Vitro, Binding Assay
Figure Legend Snippet: Biodistributions ( A ) and tumour-to-organ ratios ( B ) of [ 68 Ga]Ga-PKB2 (blue) and [ 68 Ga]Ga-PKB3 (red) at 2 h pi in PC-3 xenografted mice. Data are presented as mean ± SD (n = 4). ** indicates p < 0.01, and **** indicates p < 0.0001. The gastrointestinal tract (without stomach, pancreas and part of the small intestine) and the rest of the carcass values are given as %IA
Techniques Used:
Figure Legend Snippet: PET/CT images of [ 68 Ga]Ga-PKB2 ( A ) and [ 68 Ga]Ga-PKB3 ( B ) at 2 h pi in PC-3 xenografted mice. T indicates tumour, K indicates kidneys, and UB indicates urinary bladder. The scale of the colour intensity is in kBq/ml with maximum intensity at 50.8 kBq/ml
Techniques Used: Positron Emission Tomography-Computed Tomography